Protein Evolution

The Basic Building Blocks of Life

Director: Andrei Lupas
Assistant: Karin Lehmann
Phone: +49 7071 601-340
Fax: +49 7071 601-349

Staff: Alphabetical List | Alumni
References: Publication List


Proteins are essential building blocks of living cells; indeed, life can be viewed as resulting substantially from the chemical activity of proteins. Because of their importance, it is hardly surprising that ancestors for most proteins observed today were already present at the time of the 'last common ancestor', a primordial organism from which all life on Earth is descended. How did the first proteins arise? How can we bring a taxonomic order to the diversity of forms that evolved from them? These two questions are at the center of our scientific efforts, on which we bring to bear methods in bioinformatics, protein biochemistry and structural biology.

Research Topics

Coiled Coils