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Christiane Nüsslein-Volhard

Foto: Bettina Flitner

Telefon: +49 7071 601 487/489
Email: cnv(at)tuebingen.mpg.de

NEW: Schönheit der Tiere. Evolution biologischer Ästhetik. 120p. Mit Illustrationen von Suse Grützmacher. Verlag Matthes und Seitz, Berlin 2017. (PDF)
Animal beauty. Evolution of biological aesthetics. Translated from german by Jonathan Howard. The MIT press, Boston 2019

Research Group: Colour pattern formation

The zebrafish, Danio rerio, owing its name to the striking stereotypic pattern of horizontal blue and golden stripes, has emerged as the model organism for the genetic analysis of colour pattern formation in vertebrates. During the last years an ever increasing number of adult viable mutants with altered colour patterns have been collected, and novel approaches in lineage tracing in individual fish were developed, providing the unique oppor­tunity to access the genetic and cell bio­logical background of the complex and protracted developmental process in this species. The colour patterns in closely related Danio species are amazingly different; their variation offers a great opportunity to investigate the genetic and developmental basis of colour pattern evolution in vertebrates.

Supported by 2016 ERC Advanced grant Daniopattern.

  • Studium in Frankfurt/Main und Tübingen, Diplom in Biochemie (1968), Promotion in Genetik, Tübingen (1973).
  • Postdoc in Basel und Freiburg, Gruppenleiterin am Europäischen Labor für Molekularbiologie, Heidelberg (1978-1981) und am Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft in Tübingen (1981-1984).
  • Von 1985 bis 2014 wissenschaftliches Mitglied der Max- Planck-Gesellschaft und Direktorin am Max-Planck-Institut für Entwicklungsbiologie in Tübingen. Ihre Forschungen befassen sich mit der genetischen und molekularen Analyse der embryonalen Entwicklung bei Tieren, insbesondere der Fliege Drosophila melanogaster, sowie dem Zebrafish Danio rerio.
  • Von 2005 bis 2012 Direktorin des Friedrich-Miescher-Labors, Tübingen.
  • Seit Oktober 2014, Direktor Emeritus "Colour Pattern Formation"

Für ihre Entdeckung von Genen, die die Entwicklung von Tier und Mensch steuern, sowie den Nachweis von gestaltbildenden Gradienten im Fliegenembryo hat sie zahlreiche Auszeichnungen, Ehrendoktorate  und Preise erhalten, unter anderem den Leibnizpreis der Deutschen Forschungsgemeinschaft (1986), den Albert Lasker Medical Research Award (1991) und den Nobelpreis für Medizin (1995). Sie ist Mitglied der Royal Society (England), der National Academy (USA), des Ordens pour le mérite (Deutschland), der Leopoldina (Deutschland), der Berlin-Brandenburgischen Akademie (Deutschland), der Kurie der Wissenschaft (Österreich) und der Académie des Sciences (Frankreich). Von 2001 bis 2006 gehörte sie dem nationalen Ethikrat der Bundesregierung an. Sie gründete 2004 die Christiane Nüsslein-Volhard  Stiftung zur Unterstützung junger Wissenschaftlerinnen mit Kindern (http://www.cnv-stiftung.de). Sie war Präsidentin der Gesellschaft deutscher Naturforscher und Ärzte bis 2008 und Generalsekretärin der European Molecular Biology Organisation (EMBO) bis 2009. Von 2005 bis 2012 war sie Mitglied des Scientific Council des European Research Councils (ERC) der Europäischen Union. Seit 2013 ist sie Kanzlerin des Ordens Pour Le Mérite. 2016 erhält sie den Advanced Grant des Europäischen Forschungsrats (ERC)


Ihre Hobbys sind Musik (Gesang, Flöte, Kammermusik), Gartengestaltung und Kochen. Sie ist Vorsitzende des Kuratoriums der Internationalen Hugo-Wolf-Akademie e.V., Stuttgart.

 

Key Publications

An interview with Christiane Nüsslein-Volhard (Development 2017, PDF)
How fish color their skin: A paradigm for development and evolution of adult patterns (Bioessays 2017, PDF)
The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account (Annu. Rev. Cell. Dev. Biol. 2016, PDF)
The zebrafish issue of Development (Development 2012, PDF)
Women in science - passion and prejudice (Curr. Biol. 2008, PDF)
The bicoid morphogen papers (I): account from CNV (Cell 2004, PDF)
The Origin of Pattern and Polarity in the Drosophila Embryo (Cell 1992, PDF)
The identification of genes controlling development in flies and fishes (Nobel Lecture 1995, PDF)
The bicoid Protein Determines Position in the Drosophila Embryo in a Concentration-Dependent Manner (Cell 1988, PDF)
Mutations affecting segment number and polarity in Drosophila (Nature 1980, PDF)

 


Veröffentlichungen

über einhundertachtzig wissenschaftliche Artikel in Fachzeitschriften, einige populärwissenschaftliche Kommentare in Zeitungen (FAZ, Die Zeit).


Bücher

Das Werden des Lebens: Wie Gene die Entwicklung steuern, C.H. Beck: München 2004.

Von Genen und Embryonen, Reclam: Stuttgart 2004.

Coming to life: how genes drive development, Kales Press: USA 2006.

Mein Kochbuch: Einfaches zu besonderen Anlässen. Mit Illustrationen von Susanne Baumgarten, Insel Verlag: Frankfurt/Main 2006.

Schönheit der Tiere: Evolution biologischer Ästhetik. Mit Illustrationen von Suse Grützmacher. Matthes und Seitz Verlag, Berlin 2017

 

     

Populärwissenschaftliche Publikationen

Geistvoll genug für zwei Nobelpreise
FAZ 2020

Grenzen der Menschheit
FAZ, 2018

Grüne Gentechnik und die Freiheit der Forschung
Nachrichten Chemie 2012

Wachstum, Eskalation, Steuerung und Grenzen
Festvortrag, Tagung der GDNÄ, Tübingen, 19. - 22. September 2008

Women in Science – Passion and Prejudice
Current Biology, 11. März 2008, zur Situation von Frauen in den Naturwissenschaften.

Wann ist der Mensch ein Mensch?
Tagung: Genetik und die Zukunft des Menschen - Positionen aus dem Ethikrat 19-21.07.2002, sowie vor der juristischen Studiengesellschaft Karlsruhe, 10. Oktober 2002. Was unterscheidet die Embryonalentwicklung von Säugetieren von der anderer Tiere? Wann wird der werdende Embryo zum Menschen?

Biolandbau mit Gentech-Pflanzen
Gentechnik und Landwirtschaft, Tagesspiegel Berlin, 03. November 2016

Frauen an die Forschungsfront
Die Zeit, 2003

Kinderwunsch-Wunschkinder
Emma, 2002

Frauen in Führungspositionen in der Wissenschaft
Die Zeit, 22 Mai 2002: Zur Situation von Frauen in der Forschung.

Von Genen und Embryonen
Vortrag im Rahmen der Berliner Lektion, 25 Nov. 2001: Die Rolle der Gene bei der Entwicklung.

Wann ist ein Tier ein Tier?
Frankfurter Allgemeine Zeitung, Okt. 2001:  Was unterscheidet die Embryonalentwicklung von Säugetieren von der anderer Tiere. Wann wird der werdende Embryo zum Menschen.

Den Göttern gleich ich nicht!
Frankfurter Allgemeine Zeitung, Feb. 2001: Der Artikel erläutert den gegenwärtigen Erkenntnisstand der Genomforschung.

Genetik für Gourmets
Die Zeit, 11/1998: Offener Brief an Wolfram Siebeck über "Genfood" und Genforschung.

  1. Nüsslein, C. (1969):  Vergleich der Nukleinsäuren der Bakteriophagen 0X 174 und fd  mit der Methode der DNS-RNS-Hybridisierung, Diplomarbeit, Tübingen 
  2. Nüsslein, C. und Heyden, B. (1972):  Chromatography of RNA polymerase from E. coli on single stranded DNA-agarose columns. Biochem. Biophys. Commun.47, 282-289. 
  3. Schaller, H.,Nüsslein, C., Bonhoeffer, F., Kurz, C. and Nietzschmann, I. (1972):  Affinity chromatography of DNA-binding enzymes on single stranded DNA agarose columns. Europ. J. Biochem. 26, 474-481. 
  4. Heyden, B., Nüsslein, C. und Schaller, H. (1972):  Single RNA-polymerase binding site isolated. Nature New Biology 240, 9-12. 
  5. Nüsslein, C. (1974):  Zur spezifischen Protein-Nukleinsäure-Wechselwirkung. Die Bindung von RNS-Polymerase aus E. coli an die Replikative-Form-DNS des Bakteriophagen fd und die Charakterisierung der Bindungsstellen. Dissertation, Tübingen. 
  6. Heyden, B., Nüsslein, C. und Schaller, H. (1975):  Initiation of Transcription within RNA-polymerase binding site. Eur. J. Biochem. 55, 147-155. 
  7. Nüsslein, C. und Schaller, H. (1975):  Stabilization of promoter complexes with a single ribonucleoside triphosphate. Eur. J. Biochem. 56, 563-569. 
  8. Seeburg, P., Nüsslein, C. und Schaller, H. (1977):  Interaction of RNA Polymerase with Promotors from Bacteriophage fd. Eur. J. Biochem. 74, 107-113. 
  9. Nüsslein-Volhard, C. (1977):  A rapid method for scoring eggs from Drosophila females. Dros. Inf. Serv. 52, 166.
  10. Nüsslein-Volhard, C. (1977):  Genetic Analysis of Pattern-Formation in the Embryo of Drosophila melanogaster. Characterization of the Maternal Effect Mutant Bicaudal. Wilh. Roux's Archives 183, 249-268. 
  11. Nüsslein-Volhard, C. (1979):  Maternal Effect Mutations that Alter the Spatial Coordinates of the Embryo of Drosophila melanogaster. In "Determinants of Spatial Organisation" (I. Konigsberg and S. Subtelney eds.), Academic Press, 185-211. 
  12. Nüsslein-Volhard, C. (1979):  Pattern mutants in Drosophila embryogenesis. In "Cell Lineage, Stem Cells and Cell Determination", INSERM Symposium No. 10 (N. Le Douarin ed.), 69-82. 
  13. Lohs-Schardin, M., Cremer, C. und Nüsslein-Volhard, C. (1979):  A Fate Map for the Larval Epidermis of Drosophila melanogaster: Localized Cuticle Defects Following Irradiation of the Blastoderm with an Ultraviolet Laser Microbeam. Developmental Biology 73, 239-255. 
  14. Nüsslein-Volhard, C., Lohs-Schardin, M., Sander, K. and Cremer, C. (1980):  A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila. Nature 283, 474-476 
  15. Nüsslein-Volhard, C. und Wieschaus, E. (1980):  Mutations affecting segment number and polarity. Nature 287, 795-801. 
  16. Nüsslein-Volhard, C., Wieschaus, E. and  Jürgens, G. (1982):  Segmentierung bei Drosophila: eine genetische Analyse. Verh. dtsch. zool. Ges., 91-104. 
  17. Santamaria, P. and Nüsslein-Volhard, C. (1983):  Partial rescue of dorsal, a maternal effect mutation affecting the dorso-ventral pattern of the Drosophila embryo, by the injection of wild-type cytoplasm. The EMBO Journal 2, 1695-1699. 
  18. Anderson, K.V. and Nüsslein-Volhard, C. (1984):  Genetic analysis of dorso-ventral embryonic pattern in Drosophila. in Pattern Formation, ed. G.M. Malacinski, Macmillan, New York, 269-291. 
  19. Wieschaus, E., Nüsslein-Volhard, C. und Kluding, H. (1984):  Krüppel, a gene whose activity is required early in the zygotic genome for normal embryonic segmentation. Dev. Biol. 104, 172-186. 
  20. Nüsslein-Volhard, C., Wieschaus, E. und Kluding, H. (1984):  Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I: Zygotic loci on the second chromosome. Wilh. Roux's Archives, 193, 267-282. 
  21. Jürgens, G., Wieschaus, E., Nüsslein-Volhard, C. und Kluding, H. (1984):  Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster II: Zygotic loci on the third chromosome. Wilh. Roux's Archives, 193, 283-295. 
  22. Wieschaus, E., Nüsslein-Volhard, C. und Jürgens, G. (1984):  Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster III: Zygotic loci on the X-chromosome and fourth chromosome. Wilh. Roux's Archives, 193, 296-308. 
  23. Anderson, K.V. and Nüsslein-Volhard, C. (1984):  Information for the dorso-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature  311, 223-227. 
  24. Anderson, K.V., Jürgens, G. and Nüsslein-Volhard, C. (1985):  Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product. Cell 42, 779-789. 
  25. Anderson, K.V., Bokla , L. and Nüsslein-Volhard, C. (1985):  Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product. Cell 42, 791-798. 
  26. Nüsslein-Volhard, C., Kluding, H. and Jürgens, G. (1985):  Genes affecting the segmental subdivision of the Drosophila embryo. Cold Spring Harbour Symp. Quant. Biol. 50. "The Molecular Basis of Development." pp. 145-154. 
  27. Anderson, K.V. and Nüsslein-Volhard, C. (1986):  Dorsal-group genes in Drosophila. In: Gametogenesis and the Early Embryo (J. Gall ed.), Alan Liss. Inc. Symp. Soc. Dev. Biol. 43, 177-194. 
  28. Jürgens, G., Lehmann, R., Schardin, M. and Nüsslein-Volhard, C. (1986):  Segmental organisation of the head in the embryo of Drosophila melanogaster: A blastoderm fate map of the cuticle structures of the larval head. Wilh. Roux's Archives 195, 359-377. 
  29. Wieschaus, E. and Nüsslein-Volhard, C. (1986):  Looking at Embryos. In: Drosophila, a practical approach. D.B. Roberts ed., IRL Press, Oxford. pp. 199-226.
  30. Marcey, D. and Nüsslein-Volhard, C. (1986):  Embryology goes fishing. Nature 321, 380-381 (news and views). 
  31. Steward, R. and Nüsslein-Volhard, C. (1986):  The Genetics of the dorsal-Bicaudal-D Region of Drosophila melanogaster. Genetics 113, 113, 665-678. 
  32. Freeman, M., Nüsslein-Volhard, C. and Glover, D.M. (1986):  Giant nuclei in Drosophila embryos: gnu, a mutation resulting in the dissociation of nuclear and centrosomal divisions. Cell  46, 457-468. 
  33. Frohnhöfer, H.G., Lehmann, R. and Nüsslein-Volhard, C. (1986):  Manipulating the antero-posterior pattern of the Drosophila embryo. J. Embryol. Exp. Morph. 97 Supplement, 169-179. 
  34. Lehmann, R. and Nüsslein-Volhard, C. (1986):  Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in Drosophila. Cell 47, 141-152. 
  35. Frohnhöfer, H.G. and Nüsslein-Volhard, C. (1986):  Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid. Nature  324, 120-125. 
  36. Lehmann, R. and Nüsslein-Volhard, C. (1987):  Hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo. Devel. Biol. 119, 402-417. 
  37. Lehmann, R. and Nüsslein-Volhard, C. (1987):  Involvement of the pumilio gene in the transport of an abdominal signal in the Drosophila embryo. Nature 329, 167-170.
  38. Frohnhöfer, H.G. and Nüsslein-Volhard, C. (1987):  Maternal genes required for the anterior localization of bicoid activity in the embryo of Drosophila. Genes and Development 1, 880-890. 
  39. Nüsslein-Volhard, C., Frohnhöfer, H.G. and Lehmann, R. (1987):  Determination of antero-posterior polarity in Drosophila, Science 238, 1675-1681. 
  40. Berleth, T., Burri, M., Thoma, G., Bopp, D., Richstein, S., Frigerio, G., Noll, M. and Nüsslein-Volhard, C. (1988):  The role of localisation of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. The EMBO Journal 7, 1749-1756. 
  41. Tearle, R. and Nüsslein-Volhard, C. (1987):  Tübingen mutants and stocklist. Dros. Inf. Serv. 66., 209-256 
  42. Driever, W. and Nüsslein-Volhard, C. (1988a):  A gradient of bicoid protein in the Drosophila embryo. Cell, 54, 83-94. 
  43. Driever, W. and Nüsslein-Volhard, C. (1988b):  The bicoid protein gradient determines position in the Drosophila embryo in a concentration dependent manner. Cell 54, 95-104. 
  44. Mayer, U. and Nüsslein-Volhard, C. (1988):  A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. Genes and Development 2, 1496-1511. 
  45. Klingler, M., Erdélyi, M., Szabad, J. and Nüsslein-Volhard, C. (1988):  Function of torso in determining the terminal anlagen of the Drosophila embryo. Nature 335, 275-277. 
  46. Driever, W. and Nüsslein-Volhard, C. (1989):  The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature  337, 138-143. 
  47. Nüsslein-Volhard, C. and Roth, S. (1989):  Axis determination in insect embryos. In: Cellular Basis of Morphogenesis. CIBA Foundation Symposium 144. New York, John Wiley & Sons, 37-55. 
  48. Sprenger, F., Stevens, L.M. and Nüsslein-Volhard, C. (1989):  The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature  338, 478-483. 
  49. Driever, W., Thoma, G. and Nüsslein-Volhard, C. (1989):  Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen. Nature  340, 363-367. 
  50. Driever, W., Ma, J., Nüsslein-Volhard, C. and Ptashne, M. (1989):  Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences. Nature 342, 149-154. 
  51. Roth, S., Stein, D. and Nüsslein-Volhard, C. (1989):  A gradient of nuclear localization of the dorsal protein determines dorso-ventral pattern in the Drosophila embryo. Cell 59, 1189-1202. 
  52. St.Johnston, D., Driever, W., Berleth, T., Richstein, S. and Nüsslein-Volhard, C. (1989):  Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. Development 1989 Supplement 13-19. 
  53. Driever, W., Siegel, V. and Nüsslein-Volhard, C. (1990):  Autonomous determination of anterior structures in the early Drosophila embryo by the maternal bicoid morphogen. Development 109, 811-820. 
  54. Stevens, L.M., Frohnhöfer, H.G., Klingler , M. and Nüsslein-Volhard, C. (1990):  Localized requirement for torsolike expression in follicle cells for the development of terminal anlagen of the Drosophila embryo. Nature 346, 660-663. 
  55. Nüsslein-Volhard, C. (1990):  Determination der embryonalen Achsen bei Drosophila. Verh. Dtsch. Zool. Ges. 83, 179-195.
  56. Stevens, L.M. and Nüsslein-Volhard, C. (1991):  Development of the terminal anlagen of the Drosophila embryo depends upon interactions between the germline and the somatic follicle cells. In: J. Gerhart (ed): Cell-cell interactions in early development. New York: Wiley-Liss, Inc. pp. 145-162. 
  57. Nüsslein-Volhard, C. (1991):  Determination of the embryonic axes of Drosophila. Bateson Memorial Lecture. Development Supplement 1, 1-10. 
  58. Lehmann, R. und Nüsslein-Volhard, C. (1991):  The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo. Development 112, 679-692. 
  59. Roth, S., Hiromi, Y., Godt, D. and Nüsslein-Volhard, C. (1991):  cactus, a maternal gene required for proper formation of the dorso-ventral morphogen gradient in Drosophila. Development 112, 371-388. 
  60. Stein, D., Roth, S., Vogelsang, E. and Nüsslein-Volhard, C. (1991):  The polarity of the dorso-ventral axis in the Drosophila embryo is defined by an extracellular signal. Cell 65, 725-735. 
  61. St.Johnston, D., Beuchle, D. and Nüsslein-Volhard, C. (1991):  Staufen, a gene required to localize maternal RNAs in the Drosophila egg. Cell 66, 51-63. 
  62. Culp, P., Nüsslein-Volhard, C. and Hopkins, N. (1991):  High frequency germline transmission of plasmid DNA sequences injected into fertilized zebrafish eggs. Proc.Nat.Acad.Sci. USA 88, 7953-7957. 
  63. Ray, R.P., Arora, K., Nüsslein-Volhard, C. and Gelbart, W.M. (1991):  The control of cell fate along the dorsal-ventral axis of the Drosophila embryo. Development 113, 35-54. 
  64. Arora, K. and Nüsslein-Volhard, C. (1992):  Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. Development 114, 1003-1024.
  65. Nüsslein-Volhard, C. (1991):  Axis determination in the Drosophila embryo.The Harvey Lectures, Series 86, pages 129-148; Wiley-Liss, Inc, New York 
  66. Nüsslein-Volhard, C. (1992):  Musterbildung im Drosophila-Embryo. Nova Acta Leopoldina. Halle, NF 67, Nr. 281, 267-283. 
  67. Stein, D. and Nüsslein-Volhard, C. (1992):  Multiple extracellular activities present in the Drosophila egg perivitelline fluid are required for the establishment of embryonic dorsal-ventral polarity. Cell 68,429-440. 
  68. Isoda, K., Roth, S. and Nüsslein-Volhard, C. (1992):  The functional domains of the Drosophila morphogen dorsal:  Evidence from the analysis of mutants. Genes and Development 6, 619-630. 
  69. St.Johnston, D. and Nüsslein-Volhard, C. (1992):  The Origin of Pattern and Polarity in the Drosophila Embryo. Cell 68, 201-219. 
  70. Schulte-Merker, S., Ho, R.K., Herrmann,  B.G. and Nüsslein-Volhard, C. (1992):  The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development 116, 1021-1032. 
  71. Geisler, R., Bergmann, A., Hiromi, Y. and Nüsslein-Volhard, C. (1992):  cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IkB gene family of vertebrates.Cell 71, 613-621. 
  72. Sprenger, F. and Nüsslein-Volhard, C. (1992):  Torso receptor activity is regulated by an extracytoplasmic, diffusible ligand produced at terminal regions of the Drosophila embryo. Cell 71, 987-1001. 
  73. Sprenger, F. and Nüsslein-Volhard, C. (1993):  The terminal System of Axis Determination. In: Drosophila. M. Bate, A. Martinez-Ariaz ed. Cold Spring Harbor Laboratory Press, 365-386. 
  74. Hammerschmidt, M. and Nüsslein-Volhard, C. (1993):  The expression of a zebrafish gene homologous to Drosophila snail suggests a conserved function in invertebrate and vertebrate gastrulation. Development  119, 1107-1118. 
  75. Mullins, M. and Nüsslein-Volhard, C. (1993):  Mutational Approaches to studying embryonic pattern formation in the zebrafish. Current Opinions in Genetics & Dev. 3,648-653. 
  76. Schulte-Merker, S., van Eeden, F., Halpern, M.E., Kimmel,C.B. and Nüsslein-Volhard, C. (1994):  No tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development 120, 1009-1015. 
  77. Schulte-Merker, S., Hammerschmidt, M., Beuchle, D., K. W. Cho, E. De Robertis, and Nüsslein-Volhard, C. (1994):  Expression of the zebrafish goosecoid and no tail gene products in wild type and mutant ntl  embryos. Development 120, 843-852. 
  78. Mullins, M., Hammerschmidt, M., Haffter, P. and Nüsslein-Volhard, C. (1994):  Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Current Biology 4 , 189-202. 
  79. Isoda, K. and Nüsslein-Volhard, C. (1994):  Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen Dorsal and its inhibitor Cactus. Proc. Nat Acad. Sci USA 91, 5350-5354. 
  80. Großhans, J., Bergmann, A., Haffter, P., and Nüsslein-Volhard, C. (1994):  Activation of Pelle by Tube in the dorso-ventral signal transduction pathway of the Drosophila embryo. Nature  372, 563-567. 
  81. Nüsslein-Volhard, C. (1994):  Of flies and fishes. Science 266, 572-573 
  82. Ferrandon, D., Elphick, L., Nüsslein-Volhard, C., and StJohnston, D. (1994):  Staufen protein associates with the 3´UTR of bicoid mRNA to form particles which move in a microtubule-dependent manner. Cell 79, 1221-1232. 
  83. Nüsslein-Volhard, C. (1996):  Gradients that organize Development. Scientific American, August 1996, 54-61. 
  84. Nüsslein-Volhard, C. (1996):  The identification of Genes controlling Development in Flies and Fishes. Les Prix Nobel, Stockholm. Reprinted in: Angew. Chem. Int. Ed. Engl 35 2176-2187 und deutsche Version108, 2316-2382 
  85. Haffter, P. and Nüsslein-Volhard, C. (1996):  Large scale genetics in a small vertebrate, the zebrafish. Int. J. Dev. Biol. 40, 221-227. 
  86. Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., Van Eeden, F.J.M., Jiang, Y.-J., Heisenberg, C.-P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C. and Nüsslein-Volhard, C. (1996 ):  The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123, 1-36. 
  87. Kane, D.A., Hammerschmidt, M., Mullins, M.C., Maischein, H.M., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C.-P., Jiang, Y.-J., Kelsh, R.N., Odenthal, J., Warga, R.M. and Nüsslein-Volhard , C. (1996):  The zebrafish epiboly mutants. Development 123, 47-55. 
  88. Kane, D.A., Maischein, H.M., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M. and Nüsslein-Volhard, C. (1996):  The zebrafish early arrest mutants. Development 123, 57-66. 
  89. Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C.-P., Jiang, Y.-J., Kelsh, R.N. and Nüsslein-Volhard, C. (1996):  Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123, 81-93. 
  90. Hammerschmidt, M., Pelegri, F., Mullins, M.C., Kane, D.A., van Eeden, F.J.M., Granato, M., Brand, M., Furutani-Seiki, M., Haffter, P., Heisenberg, C.-P., Jiang, Y.-J., Kelsh, R.N., Odenthal, J., Warga, R.M. and Nüsslein-Volhard, C. (1996):  Dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development 123, 95-102. 
  91. Odenthal, J., Haffter, P., E. Vogelsang, Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammershmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Warga, R.M., Allende, M.L., Weinberg, E.S. and Nüsslein-Volhard, C. (1996):  Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development 123, 103-115. 
  92. Brand, M., Heisenberg, C.-P., Warga, R.M., Pelegri, F., Karlstrom, R.O., Beuchle, D., Picker,  A., Jiang, Y.-J., Furutani-Seiki, M., van Eeden, F.J.M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J. and Nüsslein-Volhard, C. (1996):  Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123,129-142. 
  93. Hammerschmidt, M., Pelegri, F., Mullins, M.C., Kane, D.A., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C.-P., Jiang, Y.-J., Kelsh, R.N., Odenthal, J., Warga, R.M., and Nüsslein-Volhard, C. (1996):  Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development 123, 143-151. 
  94. Van Eeden, F.J.M., Granato, M., Schach, U., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M., Allende, M.L., Weinberg, E.S. and Nüsslein-Volhard, C. (1996):  Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123, 153-164. 
  95. Brand, M., Heisenberg, C.-P., Jiang, Y.-J., Beuchle, D., Lun, K., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M., Odenthal, J., van Eeden, F.J.M. and Nüsslein-Volhard, C. (1996):  Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development 123, 179-190. 
  96. Heisenberg, C.-P., Brand, M., Jiang, Y.-J., Warga, R.M., Beuchle, D., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J. and Nüsslein-Volhard, C. (1996):  Genes involved in forebrain development in the zebrafish, Danio rerio. Development 123, 191-203. 
  97. Jiang, Y.-J., Brand, M., Heisenberg, C.-P., Beuchle, D., Furutani-Seiki, M., Kelsh, R.N., Warga, R.M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Mullins, M.C., Odenthal, J., van Eeden, F.J.M. and Nüsslein-Volhard, C. (1996):  Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123, 205-216. 
  98. Furutani-Seiki, M., Jiang, Y.-J., Brand, M., Heisenberg, C.-P., Houart, C., Beuchle, D., van Eeden, F.J.M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J. and Nüsslein-Volhard, C. (1996):  Neural degeneration mutants in the zebrafish, Danio rerio. Development 123, 229-239. 
  99. Whitfield, T.T., Granato, M., van Eeden, F.J.M., Schach, U., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M., Odenthal, J. and Nüsslein-Volhard, C. (1996):  Mutations affecting development of the zebrafish inner ear and lateral line. Development 123, 241-254. 
  100. Van Eeden, F.J.M., Granato, M., Schach, U., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M. and Nüsslein-Volhard, C. (1996):  Genetic analysis of fin formation in the zebrafish, Danio rerio. Development 123, 255-262. 
  101. Chen, J.-N., Haffter, P., Odenthal, J., Vogelsang, E., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M. and Nüsslein-Volhard, C. (1996):  Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123, 293-302. 
  102. Ransom,D.G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R.N., Brand M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Mullins, M.C. and Nüsslein-Volhard, C. (1996):  Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development  123, 311-319. 
  103. Schilling, T. F., Piotrowski, T., Grandel, H., Brand, M., Heisenberg, C.-P., Jiang, Y.-J., Beuchle, D., Hammerschmidt, M., Kane, D.A., Mullins, M.C., van Eeden, F.J.M., Kelsh, R.N., Furutani-Seiki, M., Granato, M., Haffter, P., Odenthal, J., R. M. Warga, T. Trowe and Nüsslein-Volhard, C. (1996):  Jaw and branchial arch mutants in zebrafish I: branchial arches. Development  123, 329-344. 
  104. Piotrowski, T., Schilling, T.F., Brand, M., Jiang, Y.-J., Heisenberg, C.-P., Beuchle, D., Grandel,  H., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M. and Nüsslein-Volhard, C. (1996):  Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation. Development 123, 345-356. 
  105. Kelsh, R.N., Brand, M., Jiang, Y.-J., Heisenberg, C.-P., Lin, S., Haffter, P., Odenthal, J., Mullins, M.C., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Kane, D.A., Warga, R.M., Beuchle, D., Vogelsang, E. and Nüsslein-Volhard, C. (1996):  Zebrafish pigmentation mutations and the processes of neural crest development. Development 123, 369-389.
  106. Odenthal, J., Rossnagel, K., Haffter, P., Kelsh, R.N., Vogelsang, E., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Mullins, M.C. and Nüsslein-Volhard, C. (1996):  Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio. Development 123, 391-398. 
  107. Granato, M., van Eeden, F.J.M., Schach, U., Trowe, T.,  Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.-P.,Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J. and Nüsslein-Volhard, C. (1996):  Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development 123, 399-413. 
  108. Baier, H., Klostermann, S., Trowe, T., Karlstrom, R.O.,  Nüsslein-Volhard, C. and Bonhoeffer, F. (1996):  Genetic dissection of the retinotectal projection. Development 123, 415-425. 
  109. Karlstrom, R.O., Trowe, T., Klostermann, S., Baier, H., Brand M., Crawford, A.D., Grunewald, B., Haffter, P., Hoffmann, H., Meyer, S.U., Müller, B.K., Richter, S., van Eeden, F.J.M., Nüsslein-Volhard, C. and Bonhoeffer, F.(1996):  Zebrafish mutations affecting retinotectal axon pathfinding. Development  123, 427-438. 
  110. Trowe, T., Klostermann,  S., Baier, H., Granato, M., Crawford, D.A., Grunewald, B., Hoffmann, H., Karlstrom,  R.O., Meyer, S.O., Müller, B.K., Richter, S., Nüsslein-Volhard, C. and Bonhoeffer, F. (1996):  Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio. Development 123, 439-450. 
  111. Haffter, P., Odenthal, J., Mullins, M.C., Lin, S., Farrell, M.J., Vogelsang, E., Haas, F., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.-P., Jiang, Y.-J., Kane, D.A., Kelsh, R.N., Hopkins, N., Nüsslein-Volhard, C.(1996):  Mutations affecting pigmentation and shape of the adult zebrafish. Development, Genes and Evolution 206, 260-276. 
  112. Granato, M. and Nüsslein-Volhard, C. (1996):  Fishing for genes controlling development. Curr. Op. Gen. Dev. 6, 461-468. 
  113. Bergmann, A., Stein, D., Geisler, R., Hagenmaier, S., Schmid, B., Fernandez, N., Schnell, B. and Nüsslein-Volhard, C. (1996):  A gradient of cytoplasmic CACTUS degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila . Mechanisms of Development 60, 109-123. 
  114. Ferrandon, D., Koch, I., Westhoff, E. and Nüsslein-Volhard, C. (1997):  RNA-RNA interaction is required for the formation of bicoid mRNA 3´UTR-STAUFEN ribonucleoprotein particles. EMBO Journal 16, 1751-8. 
  115. Heisenberg, C.-P., and Nüsslein-Volhard, C., (1997):  The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol 184, 85-94. 
  116. Wilsch-Bräuninger, M., Schwarz, H. and Nüsslein-Volhard, C., (1997):  A sponge like structure involved in the association and transport of maternal products during Drosophila oogenesis. J. Cell Biology, 139, 3, 817-829. 
  117. Chen, J.-N., van Eeden, F.J.M., Warren, K.S., Chin, A., Nüsslein-Volhard, C., Haffter, P., and Fishman, M. (1997):  Left-Right pattern of cardiac BMP4 may drive asymmetry of the heart in Zebrafish. Development 124, 4373-4382. 
  118. Nicolson, T., Rüsch, A., Friedrich, R.W., Granato, M., Ruppersberg,J.P. and Nüsslein-Volhard, C. (1998): Genetic analysis of vertebrate sensory hair cell mechanosensation: The zebrafish circler mutants. Neuron 20, 271-283. 
  119. Van Eeden, F.J.M., Holley, S.A., Haffter, P. and Nüsslein-Volhard, C. (1998):  Zebrafish Segmentation and Pair-Rule Patterning. Devl. Genetics 23, 65-76. 
  120. Warga, R.M. and Nüsslein-Volhard, C. (1998):  spadetail  dependent cell compaction of the dorsal zebrafish blastula. Developmental Biology 203, 116-121. 
  121. Odenthal, J. and Nüsslein-Volhard, C. (1998):  fork head domain genes in zebrafish. Dev. Genes Evol Vol. 208, 245-258. 
  122. Warga, R.M. and Nüsslein-Volhard, C. (1998):  Origin and Development of Endoderm in the Zebrafish. Development 126, 827-838. 
  123. Ribera, A.B. and Nüsslein-Volhard, C. (1998):  Zebrafish touch-insensitive mutants reveal an essential role for developmental regulation of sodium current. J Neuroscience 18, 9181-9191. 
  124. Großhans, J., Schnorrer, F. and Nüsslein-Volhard, C. (1999):  Oligomerisation of Tube and Pelle leads to nuclear localisation of Dorsal. Mechn. of Development 81, 127-138. 
  125. Holley, S.A. and Nüsslein-Volhard, C. (1999):  Somitogenesis in Zebrafish. Current Topics in Developmental Biology 47, 248-272. 
  126. Geisler, R., Rauch, R.-G., Baier, H., van Bebber, F., Broß, L., Davis, R. W., Dekens, M., Finger, K., Fricke, C., Gates, M. A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnügge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson,T., Pelegri, F., Ray, R., Rick, J., Roehl, H., Roeser, T., Schauerte, H. E., Schier, A. F., Schönberger, U.,Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W. S., Weiler, C., Nüsslein-Volhard, C. and Haffter, P. (1999):  A radiation hybrid map of the zebrafish genome. Nature Genet 23, 86-9. 
  127. Neumann, C.J., Grandel, H., Gaffield, W., Schulte-Merker, S., and Nüsslein-Volhard, C. (1999):  Transient establishment of anterior-posterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity. Development 126, 4817-4826. 
  128. Pelegri, F., Knaut, H., Maischein, H.-M., Schulte-Merker, S. and Nüsslein-Volhard, C. (1999):  A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localisation. Current Biology  9 , 1431-1440. 
  129. Odenthal, J., van Eeden, F.J.M., Haffter, P., Ingham, P. and Nüsslein-Volhard, C. (2000):  Two distict cell populations in the floor plate of thezebrafish are induced by different pathways. Developmental Biology 219, 350-363. 
  130. Luschnig, S., Krauss, J., Bohmann, K., Desjeux , I. and Nüsslein-Volhard, C. (2000):  The Drosophila SHC adaptor protein is required for signalling by a subset of receptor tyrosine kinases. Molecular Cell 5, 231-241. 
  131. Schnorrer, F., Bohmann, K. and Nüsslein-Volhard, C. (2000):  The molecular motor dynein is involved in targeting Swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nature Cell Biology 2, 185-190. 
  132. Holley, S., Geisler, R. and Nüsslein-Volhard, C. (2000):  Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity. Genes & Development 14, 1678-1690. 
  133. Knaut, H., Pelegri, F., Bohmann, K., Schwarz, H. and Nüsslein-Volhard, C. (2000): Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification.  Journal Cell Biology 149, 875-888. 
  134. Neumann, C.J. and Nüsslein-Volhard, C. (2000):  Patterning of the zebrafish retina by a wave of sonic hedgehog activity. Science 289, 2137-9. 
  135. Piotrowski, T. and Nüsslein-Volhard, C  (2000):  The endoderm plays an important role in pattering the segmented pharyngeal region in zebrafish (Danio rerio). Developmental Biology 225, 339-356. 
  136. H. Roehl and Nüsslein-Volhard, C. (2001):  Zebrafish pea3 and erm are general targets of FGF8 signaling. Current Biology 11, 503-507. 
  137. Holley, S., Jülich, D., Rauch, G.-J., Geisler, R. and Nüsslein-Volhard, C. (2002):  her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development  129, 1175-1183 
  138. Knaut, H., Steinbeisser, H., Schwarz, H. and Nüsslein-Volhard, C. (2002):  An Evolutionary Conserved Region in the vasa 3'UTR Targets RNA Translation to the Germ Cells in the Zebrafish. Current Biology 12, 1-20. 
  139. Gilmour, D.T., Maischein, H.-M. and Nüsslein-Volhard, C. (2002):  Migration and Function of a Glial Subtype in the Vertebrate Peripheral Nervous System. Neuron  34, 577-588. 
  140. Schnorrer, F., Luschnig, S., Koch, I., Nüsslein-Volhard, C., (2002):  gamma-Tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during Drosophila oogenesis. Developmental Cell 3(5), 685-696. 
  141. Maderspacher,  F. and Nüsslein-Volhard,  C. (2003):  Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions. Development 130(15), 3447-57. 
  142. Knaut, H., Werz, C., Geisler, R. and Nüsslein-Volhard, C., The Tübingen 2000 Screen Consortium (2003):  A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature   421(6920), 279-282. 
  143. Charatsi, I., Luschnig, S., Bartoszewski, S., Nüsslein-Volhard, C. and Moussian, B., (2003):  Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo. Mechanisms of Development. 120(2), 219-226. 
  144. Dekens,M., Pelegri, F., Maischein, H.-M. and Nüsslein-Volhard, C.(2003):  The maternal-effect gene futile cycle is essential for congression and mitotic spindle assembly in the zebrafish zygote. Development 130, 3907-3916. 
  145. Nüsslein-Volhard, C. (2004):  The Biocoid Morphogen Papers (I):  Account from CNV. Cell 116, S1-S5. 
  146. Luschnig, S., Moussian, B., Krauss, J. Desjeux, I., Perkovic, J. and Nüsslein-Volhard, C. 2004:  An F1  Genetic Screen for Maternal-Effect  Mutations Affecting Embryonic  Pattern  Formation in Drosophila  melanogaster. Genetics 167, 325-342. 
  147. Gilmour D., Knaut H., Maischein H.-M., Nüsslein-Volhard C. (2004):  Towing of sensory axons by their migrating target cells in vivo. Nat Neurosci. 7(5):491-492. 
  148. Lee, J.S., von der Hardt, S., Rusch, M.A., Stringer, S.E., Stickney, H.L., Talbot, W.S., Geisler, R., Nüsslein-Volhard, C., Selleck, S.B., Chien, C.B. and Roehl, H. (2004):  Axon Sorting in the Optic Tract Requires HSPG Synthesis by ext2 (dackel) and extl3 (boxer). Neuron 16, 947-60. 
  149. Sonawane, M., Carpio, Y., Geisler, R., Schwarz, H., Maischein, H.-M. and Nüsslein-Volhard, C. (2005):  Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis. Development 132, 3255-65. 
  150. Dahm, R., Geisler, R., and Nüsslein-Volhard, C. (2005):  Zebrafish (Danio rerio) genome and genetics. In Encyclopedia of Molecular Cell Biology and Molecular Medicine, R. A. Meyers, ed. (Weinheim, Wiley-VCH), vol. 15, pp. 593-626. 
  151. Moussian, B., Schwarz, H., Bartoszewski, S. and Nüsslein-Volhard, C. (2005):  Involvement of Chitin in Exoskeleton Morphogenesis in Drosophila melanogaster. J. of Morphology 264, 117-130. 
  152. Moussian, B., Söding, J., Schwarz, H. and Nüsslein-Volhard, C. (2005):  Retroactive, a Membrane-Anchored Extracellular Protein Related to Vertebrate Snake Neurotoxin-Like Proteins, Is Required for Cuticle Organization in the Larva of Drosophila melanogaster. Dev. Dyn. 233, 1056-1063. 
  153. Rojas-Munoz, A., Dahm, R. and Nüsslein-Volhard, C. (2005):  chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Dev. Biol, 288(2): 348-362 
  154. Moussian, B., Tang, E., Tonning, A., Helms, S., Schwarz, H., Nüsslein-Volhard, C., Uv, A.E. (2006):  Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization. Development, Jan;133(1):163-171. 
  155. Vogt, N., Koch, I., Schwarz, H., Schnorrer, F., and Nüsslein-Volhard, C. (2006):  The yTuRC components Grip75 and Grip 128 have an essential microtubule-anchoring function in the Drosophila germline. Development 133, 3963-3972
  156. Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F., Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Küchler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schönberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Söllner, C., Wehner, A., Weiler, C., and Nüsslein-Volhard, C. (2007):  Large-scale mapping of mutations affecting zebrafish development. BMC Genomics. Jan 9, 8-11. 
  157. Peri, F., and Nüsslein-Volhard, C. (2008):  Live imaging of Neuronal Degradation by Microglia reveals a role for v0 ATPase a1 in phagosomal fusion in vivo. Cell 133, 916-927 
  158. Harris, M. P., Rohner, N. Schwarz, H., Perathoner, S., Konstantinidis, P., and Nüsslein-Volhard, C. (2008):  Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates. PLoS Genetics 4(10): 
  159. Siegfried, K. R., and Nüsslein-Volhard, C. (2008):  Germline control of female sex determinatiuon in zebrafish. Dev. Biol. 324(2): 277-287. 
  160. Kizil C., Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL. (2009):  Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Dev Biol. 325(2):329-340. 
  161. Rojas-Munoz A., Rajadhyksha S., Gilmour D., van Bebber F., Rodriguez-Esteban C., Antos, Chr., Nüsslein-Volhard Chr., Izpisua-Belmonte J. C. (2009):  ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. Dev Biology 327(1): 177-90 
  162. Rohner N., Bercsényi M., Orbán L., Kolanczyk ME, Linke D, Brand M, Nüsslein-Volhard C, Harris MP. (2009):  Duplication of fgfr1 Permits Fgf Signaling to Serve as a Target for Selection during Domestication. Curr. Biology 19:1-6 
  163. Sonawane M, Martin-Maischein H, Schwarz H, Nüsslein-Volhard C. (2009):  Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish. Development. 136(8):1231-40. 
  164. Krauss J, López de Quinto S, Nüsslein-Volhard C, Ephrussi A.(2009):  Myosin-V regulates oskar mRNA localization in the Drosophila oocyte. Curr. Biol. 19(12):1058-63. 
  165. Reischauer S., Levesque M., Nüsslein-Volhard C. and Sonawane M. (2009):  Lgl2 executes its function as a tumor suppressor by regulating ErbB2 signaling in the zebrafish epidermis. PloS Genetics 5 (11): e1000720 
  166. Doerflinger H., Vogt N., Torres I. L., Mirouse, V., Koch I., Nüsslein-Volhard C. and St Johnston D. (2010):  Bazooka is required for polarization of the Drosophila anterior-posterior axis. Development 137: 1765 – 1773
  167. Saito K., Siegfried K. R., Nüsslein-Volhard C. and Sakai N. (2011):  Isolation and cytogenetic characterization of zebrafish meiotic prophase I mutants. Dev. Dyn. 240 (7): 1779 - 1792 
  168. Chen, Y-Y, Harris, M., Levesque, M. P., Nüsslein-Volhard, C, Sonawane, M. (2012):  Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mechanisms of Development 129, 13-23 
  169. Dooley, C. M., Schwarz, H., Müller, K., Mongera, A., Konantz, M., Neuhauss, S., Nüsslein-Volhard. C., and Robert Geisler (2012):  Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. PCMR. 12053 
  170. Nüsslein-Volhard, C. (2012):  The zebrafish issue of Development, Development, 139, 4099-4103 
  171. Mongera, A., Singh, A., Levesque, M. P., Chen, Y-Y. Konstantinidis, P., and Nüsslein-Volhard. C. (2013):  Genetic lineage labeling in zebrafish uncovers novel neural crest contributions to the head, including gill pillar cells. Development 140, 916-925. 
  172. Dooley, C. M., Mongera, A., Walderich, B., Nüsslein-Volhard, C. (2013):  On the Embryonic Origin of Adult Melanophores: The role of ErbB and Kit signalling in establishing melanophore stem cells in Zebrafish. Development, 140, 1003-1013
  173. Frohnhöfer, H G, Krauss, J., Maischein, H-M. and Nüsslein-Volhard, C. (2013):  Iridophores and their interactions with other chromatophores in the formation of the colour pattern of the zebrafish. Development 140, 2997-3007
  174. Krauss, J., Astrinides, P., Frohnhöfer, H G., Walderich, B. and Nüsslein-Volhard, C. (2013):  transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival, Biology Open 0, 1-8, bio.20135132
  175. Howe, K., Clark, M, et al. (2013):  The zebrafish reference genome sequence and its relationship to the human genome. Nature 496, 498-503
  176. Mongera, A., Nüsslein-Volhard, C. (2013):  Scales of fish arise from Mesoderm, Current Biology, Vol. 23, No 9, 338-339
  177. Perathoner, S., Daane, M. J., Henrion, U., Seebohm, G., Higdon, W. C., Johnson, L. S., Nüsslein-Volhard, C., Harris, P. M. (2014): Bioelectric signaling regulates size in zebrafish fins, PLOS Genetics, Volume 10, Issue 1: e1004080, 1-11
  178. Singh, A. P., Schach, U., Nüsslein-Volhard, C. (2014): Proliferation, dispersal and patterned aggregation of iridophores in the skin prefigure striped colouration of zebrafish. Nature Cell Biology, Volume 16, No 6, 607-614
  179. Wang, L., Mongera, A. Bonanomi, D., Cyganek, L., Pfaff, S. L., Nüsslein-Volhard, C., Marquardt, T (2014): A conserved axon type hierarchy governing peripheral nerve assembly. Development 141, 1-9 
  180. Krauss, J. Frohnhöfer, H. G., Walderich, B., Weiler, C., Irion, U., Nüsslein-Volhard, C. (2014): Endothelin signaling and stripe pattern formation in zebrafish. Biology Open 000, bio2014844, 1-7 
  181. Krauss, J., Geiger-Rudolph, S., Koch, I. Nüsslein-Volhard, C., Irion, U. (2014): A dominant mutation in tyrp1A leads to melanophore death in zebrafish. pcmr. 12272, 1-4 
  182. Mahalwar, P.; Walderich, B.; Singh, A.*; Nüsslein-Volhard, C*. (2014): Local reorganization of xanthophores fine-tunes and colors the striped pattern of zebrafish. Science, 1362, 4 
  183. Sonal, Sidhaye, J., Phatak; M., Banerjee, S., Mulay, A., Deshpande, O., Bhide, S., Jacob, T., Gehring, I., Nüsslein-Volhard, C., and Sonawane, M. (2014): Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis. PLoS Genetics, 10(9) 1004614 
  184. Irion, U., Krauss, J., Nüsslein-Volhard, C. (2014): Precise and efficient genome editing in zebrafisch using the CRISPR/Case9 system. Development, 141, 4827-4830 
  185. Irion U, Frohnhöfer HG, Krauss J, Çolak Champollion T, Maischein HM, Geiger-Rudolph S, Weiler C, Nüsslein-Volhard C. (2014) Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish. Elife, doi: 107554/eLife.05125 
  186. Singh, A., Nüsslein-Volhard, C. (2015): Zebrafish Stripes as a Model for Vertebrate Colour Pattern Formation. Current Biology 25, R81-R92
  187. Singh, A. P., Frohnhöfer, H-G, Irion, U., and Nüsslein-Volhard, C. (2015): Response to comment o "Local reorganisation of Xanthophores fine-tunes and colors the striped pattern of Zebrafish". Science, Vol. 348, No 6232, p. 297
  188. Fadeev, A., Krauss, J., Frohnhöfer, H-G, Irion, U., and Nüsslein-Volhard, C. (2015): Tight junction protein 1a regulates pigment cell organisation during Zebrafish colour patterning. eLife 2015;10.7554/eLife.06545
  189. Fadeev, A., Krauss, J., Singh A.P. and Nüsslein-Volhard, C. (2016): Zebrafish leukocyte tyrosine kinase controls iridophore establishment, proliferation and survival. Pigment Cell Melanoma Res., 2016 Jan 23. doi: 10.1111/pcmr.12454, Vol. 29, Issue 3: 284-296
  190. Irion, U., Singh, AP., Nüsslein-Volhard, C. (2016): The Developmental Genetics of Vertebrate Color Pattern Formation: Lessons from Zebrafish. Elsevier, doi:10.1016/bs.ctdb.2015.12.012 (Epub ahead of print)
  191. Walderich, B., Singh, AP., Mahalwar, P., Nüsslein-Volhard, C. (2016): Homotypic cell competition regulates proliferation and tiling of Zebrafish pigment cells during colour pattern formation, Nature Communications , doi: 10.1038/ncomms11462
  192. Frohnhöfer, H. G., Geiger-Rudolph, S., Pattky, M., Meixner, M., Huhn, C., Maischein, H.-M., Geisler, R., Gehring, I., Maderspacher, F., Nüsslein-Volhard, C., Irion, U. (2016): Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish, Biology Open 2016 : doi: 10.1242/bio.018721
  193. Singh, A. P., Dinwiddie, A., Mahalwar, P.,Schach, U., Linker, C., Irion, U., Nüsslein-Volhard, C. (2016): Pigment Cell Progenitors in Zebrafish Remain Multipotent through Metamorphosis. Developmental Cell 38, 1-15
  194. Wieschaus, E., Nüsslein-Volhard, C. (2016): The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account, Annu. Rev. Cell Dev. Biol., 32:1-46
  195. Mahalwar, P., Singh, A.P., Fadeev, A., Nüsslein-Volhard, C., Irion, U. (2016): Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish, Biology Open,1680-1690, bio.022251.
  196. Nüsslein-Volhard, C., Singh, A.P. (2017): How fish color their skin: A paradigm for development and evolution of adult patterns: Multipotency, plasticity, and cell competition regulate proliferation and spreading of pigment cells in Zebrafish coloration, Bioessays, Mar, 39(3), 201600231
  197. Eskova, A., Chauvigné, F, Maischein, H.-M., Ammelburg, M., Cerdá, J., Nüsslein-Volhard, C., Irion, U. (2017): Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment, Development 144, 2059-2069
  198. Nüsslein-Volhard, C. (2017): Gradient Models in Developmental Biology: A Historical Perspective, in Nova Acta Leopoldina: Crossing Boundaries in Science, Nr. 419, 33-44.pdf
  199. Fadeev, A. Mendoza Garcia, P., Irion, U., Guan, J., Pfeifer, K., Wiessner, S., Serluca, F., Singh, A.P., Nüsslein-Volhard, C. and Palmer, R.H.  (2018): ALKALs are in vivo ligands for ALK family Receptor Tyrosine Kinases in the neural crest and derived cells. Proc Natl Acad Sci USA 115(4):E630-E638. doi: 10.1073/pnas.1719137115