In many egg, strong asymmetries have been found that result either from sperm entry and cortical rotations or gravity. In the model, a strong asymmetry shortens the time required that one part dominates over the other. Moreover, in larger embryos the danger exists that multiple organizing regions are formed. This is illustrated in the simulations below. A substantial asymmetry in the ability of the cells to perform the self-enhancement (blue) can lead to a single maximum (green, the red ring is the inhibitor distribution).