In contrast, if the antagonistic reaction results from an inhibitor that is produced under activator control, periodic patterns form by insertion of new maxima into the enlarging interstices, rather than by splitting of existing maxima (see Insertion of new maxima
; for more details of this behavior, see Meinhardt, 2003 ). The different behavior is based on an upper bound of the self-enhancing reaction inherent in the activator - depleted substrate system since the activation can no longer increase if all precursor molecules are used up. After introduction of a saturation in an activator-inhibitor system, both systems behave very similar. A feature of satuating systems that is important for many biological applications is that maxima can easier move to a preferential position and they can split.