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Protein Evolution – The Basic Building Blocks of Life

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Director:
Andrei Lupas
Secretary:
Karin Lehmann
Phone:
+49 7071 601-340
Fax:
+49 7071 601-349
Staff:
Alphabetical List

Introduction

Proteins are essential building blocks of living cells; indeed, life can be viewed as resulting substantially from the chemical activity of proteins. Because of their importance, it is hardly surprising that ancestors for most proteins observed today were already present at the time of the 'last common ancestor', a primordial organism from which all life on Earth is descended. How did the first proteins arise (Protein Evolution)? How can we bring a taxonomic order (Protein Classification) to the diversity of forms that evolved from them? These two questions are at the center of our scientific efforts, on which we bring to bear methods in bioinformatics, protein biochemistry and structural biology.
 
Publications

Research

Protein Evolution
Andrei Lupas
Protein Classification
Andrei Lupas
Cellular Protein Folding and Unfolding: Chaperonins and AAA ATPases
Jörg Martin
The Bacterial Cell Surface
Dirk Linke
Specifiicity in Signaling Networks
Yvonne Groemping

Resources