The Department of Biochemistry at the Max Planck Institute for Developmental Biology in Tübingen offers:
PhD and post-doctoral positions in Molecular and Cellular Biology / Biochemistry / Structural Biology
The Department of Biochemistry studies the molecular mechanisms underlying post-transcriptional gene regulation, including translational regulation, mRNA quality control, mRNA degradation, miRNA-mediated gene silencing as well as retrotransposition. We use an integrative approach combining molecular and cellular biology with biochemistry and structural biology. In particular, we use biophysical methods combined with X-ray crystallography and lower resolution approaches (SAXS, negative stain EM) to obtain structural information on macromolecular complexes involved in post-transcriptional mRNA regulation. Structural studies are combined with functional assays at the cellular level using among others gene knockouts, complementation assays and RNA Seq.
The institute offers modern instrumentation and facilities to carry out protein expression, purification and crystallization, including eukaryotic cell culture. Equipment for biophysical studies includes NMR, MST, SwitchSense and ITC technologies. Additional research facilities comprise light microscopy and next generation sequencing. Furthermore, the institute is planning to invest in a substantial upgrade of the current EM facilities with the purchase of a state-of-the-art microscope for single particle cryoEM studies.
The Max Planck Society is one of the world’s leading research organizations. The institute is located in Tübingen, a picturesque university town located approximately 30 minutes drive south of Stuttgart in south-west Germany.
We are looking for highly motivated candidates who are enthusiastic to work in an ambitious and multidisciplinary team. A key requirement for the positions is expertise in molecular and cellular biology, biochemistry and/or structural biology. A background in RNA biology or experience in protein expression, purification and crystallization will be considered an asset.
Applications including letter of motivation, detailed CV, a brief description of previous work, as well as the names and contact information of two referees should be sent before May 31, 2017, preferably electronically, to Dr. Elisa Izaurralde (email: position.dept2[at]tuebingen.mpg.de