The Pristionchus pacificus proteome

With the completion of the P. pacificus genome project, we have started a collaboration with the Proteome Center Tübingen (PCT) and initiated a P. pacificus Proteome project. The PCT is part of the Interfaculty Institute for Cell Biology, Tübingen University, and is headed by Prof. Dr. B. Maçek.

The P. pacificus Proteome project has several major aims, such as
1.) the generation of a comprehensive catalogue of the P. pacificus proteome,
2.) the comparison of the P. pacificus secreted proteins of growing larvae versus dauer larvae, and also of different other nematodes, including parasitic and free-living nematodes,
3.) the analysis of P. pacificus ability to detoxify emphasizing in differential expression of glutathione-s-transferases.



Scientist(s) involved:

Selected References:

Borchert, N., Dieterich, C., Krug, K., Schütz, W., Jung, S., Nordheim, A., Sommer, R.J. & Macek, B. (2010): Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models. Genome Res., in press.