Felix Tritschler

Department 2 (Biochemistry)

Molecular and Cellular Biology

MPI for Developmental Biology, Spemannstr. 35 / II, 72076 Tübingen, Germany

Biography

• 2004 Diplom Biochemistry, University of Tübingen, Germany
• Research associate at the Physiological Institute and the Hertie Institute for Clinical Brain Research, Tübingen
• since 2006 PhD student at MPI for Developmental Biology, Dept of Biochemistry, Tübingen, Germany

Publications

Tritschler F, Braun JE, Motz C, Igreja C, Haas G, Truffault V, Izaurralde E & Weichenrieder O (2009) DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proc Natl Acad Sci U S A 106, 21591-96. PubMed

Eulalio A, Tritschler F, Büttner R, Weichenrieder O, Izaurralde E & Truffault V (2009) The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Nucleic Acids Res 37, 2974-83. PubMed

Tritschler F, Braun JE, Eulalio A, Truffault V, Izaurralde E & Weichenrieder O (2009) Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Mol Cell 33, 661-8. PubMed

Eulalio A, Tritschler F & Izaurralde E (2009) The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing. RNA 15, 1433-42. PubMed

Tritschler F, Eulalio A, Helms S, Schmidt S, Coles M, Weichenrieder O, Izaurralde E & Truffault V (2008) Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Mol Cell Biol 28, 6695-708. PubMed

Tritschler F, Eulalio A, Truffault V, Hartmann MD, Helms S, Schmidt S, Coles M, Izaurralde E & Weichenrieder O (2007) A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Mol Cell Biol 27, 8600-11. PubMed